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'Agriculture, Environment and the Developing World: A Future of PCR': Part 2: Examples from Tropical Agriculture 1: Sugarcane Plenary lecture by Richard Jefferson, CEO Cambia, Cold Spring Harbor, September, 1994. In this 1994 presentation, Professor Richard Jefferson introduces the concept of the hologenome - the idea that microbes are not only ubiquitous, but that they may also be the most important component that drives the evolution of macro-organisms. Hologenomes are essential to appreciating the natural variation responsible for much of the world's agricultural adaptation and performance, and the intrinsic impossibility of extrapolating from model systems. See 'The Hologenome & Hologenomics: a different lens on evolution,' http://blogs.cambia.org/raj/index.php/2007/09/06/the-hologenome-hologenomics/. Available as number 6 in a series of 7 VHS recordings, 'A Decade of PCR: Celebrating 10 Years of Amplification,' released by Cold Spring Harbor Laboratory Press, 1994. ISBN 0-87969-473-4. http://www.cshlpress.com/default.tpl?action=full&cart=12589496893550441&--eqskudatarq=307&newtitle=A%20Decade%20of%20PCR%3A%20Celebrating%2010%20Years%20of%20Amplification